Emerging Treatments

PRP Therapy for the Vulva: The O-Shot Explained

Platelet-Rich Plasma, including the popular 'O-Shot', is a hot topic in aesthetic gynaecology. We look at the facts behind the hype.

Op. Dr. Berra Önsoy — Consultant Obstetrician & Gynaecologist
Medically written & reviewed by
Op. Dr. Berra Önsoy · Consultant Obstetrician & Gynaecologist
Istanbul, Turkey · 29 years of clinical practice · 4 min read · Consults in English & Turkish

Istanbul University Cerrahpaşa (English) MD, 1997. Ob-Gyn residency at Taksim Training & Research Hospital (2001). Private practice in Istanbul focused on endometriosis, myoma surgery, high-risk pregnancy and aesthetic gynaecology.

Clinical focus
  • Endometriosis surgery
  • Myoma (fibroid) surgery
  • High-risk pregnancy
  • Aesthetic gynaecology
  • HPV & colposcopy
Last medically reviewed: 15 January 2026View full clinical credentials·Verify on:drberraonsoy.cominstagram.com
Key takeaways
  • PRP therapy uses growth factors derived from a sample of your own blood to theoretically stimulate tissue healing and regeneration.
  • In gynaecology, it is marketed as the 'O-Shot' for sexual enhancement and also used to treat skin conditions like Lichen Sclerosus.
  • While it is generally considered safe, there is currently limited high-quality scientific evidence to support many of the marketing claims made about it.
  • This treatment is only available in private clinics in cities like London, Manchester, and Birmingham; it is not offered on the NHS.

What is Platelet-Rich Plasma (PRP)?

Platelet-Rich Plasma, or PRP, is a concentrate derived from your own blood. A small blood sample is taken and spun in a centrifuge to separate the platelets, which are cell fragments rich in potent growth factors.

The theory is that when this concentrated plasma is injected back into tissue, these growth factors can help to stimulate cell regeneration, improve blood flow, and build new collagen.

PRP in Gynaecology: The 'O-Shot'

In aesthetic gynaecology, PRP is most famously used in a procedure branded as the 'O-Shot'. This involves injecting the PRP into the area around the clitoris and the upper vaginal wall.

The treatment claims to heighten sexual arousal, improve orgasm intensity, and increase lubrication. It is also used 'off-label' to treat certain vulval skin conditions like Lichen Sclerosus and to improve the general texture and tone of the vulvar skin.

The Evidence vs. The Hype

While PRP has a proven role in other fields of medicine like orthopaedics, its use in gynaecology is still emerging. Many of the claims are based on small studies or anecdotal patient reports rather than large, robust clinical trials.

While many women report positive outcomes, the scientific community is still working to establish exactly how effective it is, for whom it works best, and how it compares to other treatments. It is important to approach it with realistic expectations.

Is It a Safe Treatment?

Because PRP is derived from your own body, the treatment is considered very safe with a low risk of allergic reaction or side effects. The main risks are related to the injection itself, such as minor pain, bruising, or swelling.

This is not a treatment available on the NHS and is offered by many private clinics. It's crucial to choose a qualified medical professional with experience in intimate injections to ensure the procedure is performed safely and correctly.

Frequently asked questions

What does the O-Shot claim to do?

The 'O-Shot' is a specific application of PRP where it is injected into the clitoris and the anterior vaginal wall. It claims to improve sexual arousal, intensify orgasms, and increase natural lubrication.

Is the O-Shot a proven medical treatment?

Currently, it is not considered a mainstream medical treatment. While there is a lot of anecdotal praise for it, there is a lack of large-scale, peer-reviewed clinical studies to definitively prove its effectiveness compared to other treatments. Research is ongoing.

How long do the effects of PRP last?

The longevity of results is not well-established and varies significantly between individuals. Most clinics suggest that any perceived benefits might last from several months to over a year, with repeat treatments needed to maintain them.

Is the injection painful?

A strong topical numbing cream is applied to the area before the injections, so the procedure itself should involve minimal discomfort. You may feel a brief pinch or pressure.

Can I get this treatment on the NHS?

No. This treatment is not supported by NICE (National Institute for Health and Care Excellence) guidelines for these indications and is not available on the NHS. It is only offered in private aesthetic clinics.

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