INFERTILITY INVESTIGATIONS

Male Factor Infertility: The First Checks To Make

When a couple is struggling to conceive, it's essential to investigate all potential causes. Male factor contributes to roughly half of cases, and because it's so simple to check, it should always be the starting point.

Op. Dr. Berra Önsoy — Consultant Obstetrician & Gynaecologist
Medically written & reviewed by
Op. Dr. Berra Önsoy · Consultant Obstetrician & Gynaecologist
Istanbul, Turkey · 29 years of clinical practice · 4 min read · Consults in English & Turkish

Istanbul University Cerrahpaşa (English) MD, 1997. Ob-Gyn residency at Taksim Training & Research Hospital (2001). Private practice in Istanbul focused on endometriosis, myoma surgery, high-risk pregnancy and aesthetic gynaecology.

Clinical focus
  • Endometriosis surgery
  • Myoma (fibroid) surgery
  • High-risk pregnancy
  • Aesthetic gynaecology
  • HPV & colposcopy
Last medically reviewed: 15 January 2026View full clinical credentials·Verify on:drberraonsoy.cominstagram.com
Key takeaways
  • Male factor infertility contributes to around 50% of all cases of heterosexual couple infertility.
  • A semen analysis is the cornerstone test and should be one of the very first investigations.
  • The test assesses sperm count (how many), motility (how they move), and morphology (their shape).
  • Lifestyle factors like diet, smoking, and alcohol can have a significant impact on sperm health.

Why We Always Check Male Fertility First

Fertility is about teamwork, and we need to check both partners. A common misconception is that infertility is primarily a female issue. In reality, a male factor is a contributing cause in about half of all couples who struggle to get pregnant.

The main reason we start with the male partner is simple: the test is non-invasive, quick, and gives us a huge amount of information. Before a woman undergoes more complex and invasive investigations, a simple semen analysis can often give us a clear direction.

The Semen Analysis: What We Look For

The semen analysis is the gold standard test for male fertility. The sample is produced and checked in a laboratory, where scientists look at three key parameters under a microscope.

First is concentration, or 'sperm count' – the number of sperm per millilitre. Second is motility, which measures what percentage of the sperm are moving effectively. Finally, we assess morphology, which is the shape and structure of the sperm. These three factors together give us a good picture of sperm health.

Common Causes of Male Infertility

The causes of male infertility can be varied. They can range from underlying medical conditions, such as the effects of a previous infection or surgery, to genetic issues. However, very often, the cause is linked to lifestyle factors.

Things like smoking, excessive alcohol consumption, poor diet, being overweight, and recreational drug use can all negatively impact sperm production and function. The good news is that many of these are reversible with simple changes.

Frequently asked questions

How do we arrange a semen analysis?

The first step is for your partner to see his GP. The GP can discuss any relevant history and arrange the test at a local hospital or fertility clinic. It's a straightforward process that is routinely available on the NHS.

Can lifestyle changes really make a difference to sperm quality?

Yes, significantly. Sperm takes about three months to develop, so positive changes to diet, exercise, and habits like smoking or excessive drinking can have a real impact on the quality of sperm produced three months from now.

What happens if the semen analysis results are abnormal?

It doesn't mean you can't conceive. The first step is to repeat the test after about three months to confirm the result, while also making positive lifestyle changes. If the results are still not ideal, your GP will refer you to a specialist for further investigation and to discuss options like IUI or IVF.

Does wearing tight boxers really affect fertility?

The evidence is not conclusive, but the testes need to be slightly cooler than the rest of the body to produce sperm effectively. It's a simple change to switch from tight briefs to looser-fitting boxers, and it may be beneficial, so it's a reasonable recommendation.

Could a doctor-led plan help you?

A 30-minute video consultation with Dr Berra Önsoy — reviewing your case and giving you a clear, personalised next step.

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